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Studies have demonstrated the efficacy of GLP-1RAs for glycemic control and their potential cardiovascular [41] and renal protective effects [42]

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found that intraperitoneal injection of exendin-4 increased the number of BrdU-positive progenitor cells in the subventricular zone (33), indicating that exendin-4 could compensate for the loss of dopaminergic neurons in the PD model by promoting the formation of substantia nigra neurons

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