A limitation of the current review is that it focused on indirect comparisons of 24-h continuous monitoring studies that differed in terms of study population (e.g., obese or not-obese, ambulatory or not-ambulatory), study treatment (e.g., continuous intravenous infusion, or oral administration) and timing of assessment after variable duration of study treatment
Others may allow a direct switch if dosing intervals align and side effects are minimal
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Any signs of cloudiness, haziness, floating specks, or a milky appearance are massive red flags