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Recently, several pieces of evidence have been provided in favor of the role of the uremic state which interferes with the binding of calcitriol to VDR (60) and with the nuclear uptake of the hormone-receptor complex (67)

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doi: 10.3748/wjg.v30.i23.2964 31 GuanBTongJHaoHYangZChenKXuHet al

Concentration Matters, Not the Color The effectiveness of a GHK-Cu serum is determined by the concentration of the copper peptides, not by how blue the solution is