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What are some of the purported, reported, and known mechanisms

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L-carnitine protects C2C12 cells against mitochondrial superoxide overproduction and cell death

The Keap1 cysteine residue-mutant and electrophile-modified Keap1, both of which have lost the ability to ubiquitinate Nrf2, often retain the capacity to bind with Nrf2

Besides neurons, astrocytes and microglia express GLP-1Rs (see Vrang and Larsen, 2010 for a general overview) (Merchenthaler et al., 1999