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They compared exercise alone, exercise plus liraglutide, or liraglutide alone in people without diabetes.[ref] Works even at lower doses: A 2025 study found that people who werent as consistent in taking daily doses or in taking the prescribed amount still had significant weight loss.[ref] 9 Natural supplements and diet changes that increase GLP-1 Access this content: An active subscription is required to access this content

doi: 10.3389/fendo.2019.00155

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Clinical trials show no statistically significant difference in weight loss speed between morning and evening GLP-1 injections when dosing is otherwise identical

Real-world data from weight-loss clinics show that 1525% of patients on sustained GLP-1 therapy develop deficiencies in vitamin B12, iron, or calcium within 612 months if intake and absorption are not actively managed

[DOI] [PubMed] [Google Scholar] 8.Agouridis AP, Filippatos TD, Derdemezis CS, Mikhailidis DP, Elisaf MS