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10.1071/an21395 [DOI] [Google Scholar] DeGroot A

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Hypoglycemia is also a rare manifestation of PMM2-CDG and hyperinsulinism has been identified as its main cause in 43% of patients reported in literature (132)

In hypertensive states, mitochondria generate excessive ROS due to electron transport chain (ETC) disruption, particularly at complexes I and III, coupled with reduced antioxidant defenses (e.g., Mn-SOD) (Grossini et al., 2025)