Although some of the above described combination preparations seemed to be effective in the context of reducing ES-induced impairments, due to the variety in nutrients, stressors and supplementation duration/period, no definite conclusions can be drawn
Statistical analysis In conducting the meta-analysis, we employed the R programming language (Version 4.1.3, R for Windows, Vienna, Austria) along with RStudio (Version 1.1.463, Posit PBC, Boston, MA, USA), utilizing the 'tidyverse' and 'meta' statistical packages
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2 Methods 2.1 Animals and procedures The animal experimental procedures were approved by the Animal Care and Use Committee of Oujiang Laboratory (SYXK2023-0047, OJLAB22121609), and were carried out in strict accordance with the National Institutes of Health Guidelines for the Use of Laboratory Animals
Blood pressure, cholesterol, and arterial stiffness all improved, suggesting direct protection of blood vessels and heart muscle beyond weight reduction alone
Serum bilirubin pigments covalently linked to albumin