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Tirzepatide's gastric-slowing effect reduces that bioavailability to an estimated 1218% based on similar studies of nutrient absorption during GLP-1 therapy

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Multivitamin side effects may include stomach upset if taken on an empty stomach or potential nutrient excess with high doses

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Impairment of incretins (secretion/activity) has been described in several IR states beyond T2D, such as obesity, prediabetes, and polycystic ovary syndrome (PCOS) [34, 41, 43]