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Nevertheless, taken together, these studies indicate that DPP-4 may be able to influence fat and liver biology via both direct and indirect pathways, and suggest, therefore, that metabolic control could be perturbed if DPP-4 levels change

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This effect likely relates to the peptide's GABAergic and anti-NMDA activities

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The peptide's development focused on enhancing hydrophobicity, decreasing hydrogen bonding potential, and increasing metabolic stability, resulting in a compound with an exceptionally long plasma half-life of approximately 335 minutes