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Roles of CDK/Cyclin complexes in transcription and pre-mRNA splicing: Cyclins L and CDK11 at the cross-roads of cell cycle and regulation of gene expression

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nal , Cansz D, Beler M, Sezer Z, Gzel E, Emekli-Alturfan E

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In glioblastoma, glucose-driven metabolic reprogramming induces lactylation of the DNA-repair scaffold XRCC1, strengthening its interaction with PARP1 and conferring resistance to temozolomide and radiotherapy [84]