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Furthermore, SOD1 undergoes the cyclic reduction and oxidation of copper ions (Mccord and Fridovich, 1969), and it also inhibits oxidative inactivation of nitric oxide to prevent peroxynitrite formation (Harraz et al., 2008)

Cell surface area measurements Primary murine cardiomyocytes were fixed for 20 min with 4% paraformaldehyde and sealed for 2 h using QuickBlock Immunostaining Closure Solution (Beyotime, Shanghai, China) at room temperature

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(14) In the end, the scholars observed that TB-500, when combined with cardiac reprogramming techniques, might collaboratively reduce potential harm to cardiac cells and foster its regeneration by activating inherent cells within the cardiac region