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Cryo-EM samples were prepared by applying 3 l of the aforementioned complex to a glow-discharged (PELCO easiGlow, 45 s in air at 15 mA and 0.37 mbar) holey carbon grid (C-flat, 2/1-3C-T) and vitrified using the FEI Vitrobot Mark IV System (Thermo Fisher Scientific)

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Reducing fats and sugars, and including more fibre and protein can help you feel fuller for longer and reduce snacking/cravings

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Weight loss can be challenging for many people, even those who maintain consistent diet and exercise routines