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Participants were randomly assigned in a 1:1 ratio to receive a weekly dose of either the maximum tolerated dose of tirzepatide (titrated up to 10 or 15mg) or the maximum tolerated dose of semaglutide (titrated up to 1.7 mg or 2.4mg)
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Semaglutide is most commonly taken as a once-weekly injection
Supportive secondary endpoints were not included in the statistical testing hierarchy and were: achievement of weight loss of 20% at week 104
It does this by slowing down the process of gastric emptying, which means food stays in your stomach longer, making you feel full for extended periods
To prevent hypokalemia, regular blood tests to monitor potassium levels are beneficial, especially if youre taking semaglutide and other medications that affect electrolytes
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