These metabolic studies jointly suggest that wtIDH1 enhances antioxidant defense through the generation of NADPH and impacts metabolic pathways at the level of the TCA cycle through the generation of IDH1-derived KG
We observed that spleen tissue has cystine content at 1045 M which is even less than in plasma (Supplementary Fig
Activation of pattern recognition receptor-mediated innate immunity inhibits the replication of hepatitis B virus in human hepatocyte-derived cells
10.3390/jcm9072095 [DOI] [PMC free article] [PubMed] [Google Scholar] 260.Yang L, Xie X, Tu Z, Fu J, Xu D, Zhou Y
Chronic diseases including diabetes, HIV, and hepatic cirrhosis impair antioxidant capacity
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