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SainiRKPrasadPLokeshVShangXShinJKeumY-Set al

Moreover, three significant urinary metabolites (succinic acid, glutamic acid, and benzeneacetic acid) exhibited the highest specificity and sensitivity of prediction power according to machine learning methods (almost=1).These three significant features also achieved good performance among the seven machine learning algorithms using external validation ( Supplementary Table 1 ), pointing out their potential as urinary biomarkers for ovarian cancer

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Moreover, it downregulated oxidative stress-related pro-inflammatory proteins, such as p38 MAPK and NF-B, and decreased the Bax/Bcl-2 ratio, thus reducing apoptosis and enhancing mucosal cell survival

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In the case of histamine intolerance and MCAS, that means identifying what triggered the cycle of inflammation, histamine release, and immune reactions in the first place