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Glutaredoxins employ parallel monothiol-dithiol mechanisms to catalyze thiol-disulfide exchanges with protein disulfides

It plays a critical role in recycling other antioxidants like vitamins C and E, maintaining liver health, and defending against oxidative stress that accelerates aging

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Furthermore, it resulted in tumours with reduced levels of cysteine-dependent metabolites (hypotaurine) and increased levels of ophthalmic acid, which is synthesized in the absence of cysteine 32,33 (Fig

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doi: 10.3109/10408449509089885