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Unlike sildenafil, a phosphodiesterase-5 inhibitor that produces erections using a peripheral effect, it does not require sexual stimulation, and its effect is longer-lasting

Metoprolol should be used with caution in people who have a history of anaphylactic reactions

Patients are encouraged to report suspected side effects to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)

Microbial dysbiosis is known to affect intestinal short chain fatty acid (SCFA) levels 22,23

But, it is not used for everyone, because it can lead to potential side effects