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By preventing this degradation, DPP-4 inhibitors increase the levels and prolong the activity of incretin hormones, leading to enhanced insulin secretion and suppressed glucagon release in a glucose-dependent manner

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A central hallmark of atherosclerosis is foam cell formation characterized by uncontrolled lipoprotein accumulation within macrophages (62)

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This resistance has been linked to chronic health conditions such as heart disease, fatty liver disease, and cognitive decline