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Now, the observation that oral semaglutide was being initiated in patients with a relatively low prevalence of complications and use of insulin is reassuring that the oral delivery route is helping re-positioning GLP-1RA earlier in the natural course of T2D

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doi: 10.1073/pnas.2321972121 51 HanX.SuR.HuangX.WangY.KuangX.ZhouS.et al

PMID: 10470368 DOI: 10.1016/s0065-2571(98)00029-6