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The receptors most responsible for MCA include: FceR1A, FceR1B - which respond to allergens such as pollen ADGRE2 - activated by friction or scratching, resulting in red markings on the skin

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Neurotrophins, such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), are synthesized by neurons of the central nervous system (CNS) and ANS as small active peptides that, upon coupling with their receptors (tropomyosin receptor kinase A and B), play a substantial role in neuronal remodeling (Keefe et al., 2017)