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Further, long-term use of acid-reducing drugs and the anti-diabetes drug metformin and repeated exposure to nitrous oxide have been implicated in vitamin B 12 deficiency (see Drug interactions)

I use a 1 to 1 needle, assuring a deep injection

During the loading phase , patients typically receive 1mg of hydroxocobalamin intramuscularly three times per week for two weeks (six injections total)

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