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Liraglutide reverses pronounced insulin-associated weight gain, improves glycaemic control and decreases insulin dose in patients with type 2 diabetes: a 26 week, randomised clinical trial (ELEGANT)
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Pulsatile GH secretion physiology research Physiological GH secretion occurs in discrete high-amplitude pulses driven by hypothalamic GHRH/somatostatin alternation
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Helen Knight, director of medicines evaluation at NICE, said: 'For some people losing weight is a real challenge which is why a medicine like semaglutide is a welcome option.' Dietitian Dr Duane Mellor, of Aston Medical School at Aston University in Birmingham, said: 'It is important to remember that semaglutide works alongside and supports healthy lifestyle changes
However, most studies have focused on specific patient subgroups, limiting the generalizability of the findings to the broader population of individuals with obesity
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