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Neuroprotection and CNS modulation spinal cord injury models, dopaminergic and serotonergic interactions

Dong Y, Saal D, Thomas M, Faust R, Bonci A, Robinson T et al (2004)

Available data suggest that under hypoxichypoglycemic conditions of ischemic stroke, oligodendrocytes are particularly vulnerable owing to their high iron load, low levels of reduced glutathione, elevated oxidative metabolic rate, abundant lipid and sphingolipid content, and the high permeability of their glutamate receptors (S

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TB-500 is studied primarily for cell migration through actin regulation the synthetic Thymosin Beta-4 fragment's mechanism involves binding G-actin and influencing the cytoskeletal dynamics that drive cells to physically move toward sites of injury

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