Apart from zidovudine used in the treatment of HIV infection, antimalarials, oestrogen, ketoconazole, clofazimine, and imatinib may mediate the development of oral mucosal melanin hyperpigmentation [12, 38]
doi: 10.1016/j.cmet.2022.02.015 29 GisondiPFostiniACFossIGirolomoniGTargherG
Extension studies have shown that weight loss is generally maintained with continued therapy, though significant weight regain occurs upon discontinuationan important consideration for long-term treatment planning
2.1.4 Improved angiogenesis in polycystic ovary syndrome Among other heterogeneous features, abnormal angiogenesis is one of the characteristics of PCOS
This antioxidant reduces melanin production, resulting in a lighter, more even complexion over time
Specifically, Phase 3 trials are also exploring its efficacy in treating osteoarthritis and metabolic dysfunction-associated steatohepatitis (MASH), formerly known as fatty liver disease