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Furthermore, adipose tissue macrophages (ATMs) play an important role in clearing dead or over-expanded adipocytes [39], which will be discussed in a later section

A longer study period is also recommended to confirm whether these benefits are sustained and clinically relevant in disease prevention [38]

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Myo-inositol gives similar improvements in cycle regularity, ovulation rates, androgen levels and insulin sensitivity compared to metformin in numerous head-to-head studies but with far fewer side effects (no nausea, diarrhoea or metallic taste)

Thiamine has not been associated with fetal harm