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When glutathione is incorporated into a topical formula like Glutafine Face Wash, heres what it does: Inhibits tyrosinase , the enzyme responsible for melanin production Neutralizes free radicals that cause oxidative damage and skin aging Shifts melanin from eumelanin (darker) to phaeomelanin (lighter) , creating a gradual brightening effect Supports skin repair at the cellular level A clinical study published in the Journal of Clinical and Aesthetic Dermatology found that participants using topical glutathione twice daily showed a significant reduction in melanin index after just four weeks