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Beyond iron handling, NRF2 modulates the GSH antioxidant system by inducing the expression of enzymes required for GSH biosynthesis, such as glutamatecysteine ligase catalytic and modifier subunits (GCLC/GCLM), glutathione synthase (GSS), and the cystine/glutamate antiporter subunit SLC7A11 [114]

34 The neuroprotective effect of ALC in CTS was tested in a multicenter, examiner-blinded, clinical and neurophysiological study totaling 82 patients

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