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Differential diagnosis For other causes of 5-oxoprolinuria, beside glutathione synthetase deficiency and 5-oxoprolinase deficiency [9, 29], please see Table 1

A deficiency of insulin or a lack of sensitivity of peripheral receptors to insulin lead to hyperglycemia

Glutathione regulates melanin production by inhibiting tyrosinase, the enzyme that triggers pigmentation

Products claiming 95% or higher purity indicate false labelling or synthetic spiking [13]

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So, one biological form of oxidized cysteine is when it is bound to a metal or another cellular oxidant (Figure 3)