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This model entails that, upon androgen binding, AR is activated, loses interactions with chaperone proteins, translocates to the nucleus where it binds as a dimer to AREs and activates or represses transcription of its target genes with the assistance of a large interactome of regulatory proteins (Fig

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Accessed December 10, 2011

This process, known as reconstitution, isn't just a formality

Patients, patient representatives, and care partners will share their experiences with nonhealing chronic wounds during the meeting, and attendees will learn how the condition affects patient health, current treatments, and clinical trial considerations

(1997) and Garcia et al