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Melanin is a pigment found in the skin responsible for the darkening of skin tone as it consists of blackish-brown eumelanin and reddish-yellowish pheomelanin

Cells begin producing keratin and lipids as they move up to strengthen the skin and contribute to the protective barrier

For instance, galangin downregulated TRPV1, CGRP, and substance Pkey nociceptive markers involved in visceral hypersensitivity and gastric pain in models of ethanol-induced mucosal injury

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Glutathione exists primarily in it's reduced form GSH

Reference: Michiels C et al