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Clinical data shows that Zepbound can significantly decrease the effectiveness of oral birth control pills, especially during the first four weeks of treatment or after a dose increase

The SURPASS and SURMOUNT trial programs Tirzepatide was evaluated in over 10,000 participants across the SURPASS (type 2 diabetes) and SURMOUNT (obesity) trial programs

The effect of SPT on biological and physiological development processes is still unclear

Elevated levels of FSH and LH are associated with male infertility

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however, this is FDA staff's proposed position going into the meeting, not a final action, and the committee's discussion, any vote, and FDA's ultimate decision are still pending, so the outcome of the review is not yet known