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There is also the risk of dangerous interactions with medications for cardiovascular disease or other chronic conditions

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Mendelian randomization analysis also showed an inverse relationship between GLP-1 receptor expression and severe DR, indicating the potential of GLP-1RAs in reducing the risk of DR in type 2 diabetes patients ( This seemingly controversial impact of GLP-1RAs on DR may be because most trials focused on microvascular and cardiovascular outcomes rather than DR

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