If tiredness continues beyond the initial months of treatment, becomes progressively worse, or significantly impairs daily functioning, it may indicate inadequate nutrition, dehydration, electrolyte disturbances, uncontrolled diabetes, thyroid dysfunction, anaemia, or other medical conditions requiring investigation
For more comprehensive advice on managing skin changes during weight loss, explore our guide on Skin Laxity After Weight Loss: Causes, Prevention, And Treatments
Decreased appetite: This is technically a therapeutic effect, not a side effect, but it can feel extreme during the first few weeks at a new dose
BLACK BOX WARNING: Risk of Thyroid C-Cell Tumors In animal studies, tirzepatide caused thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)
Just under 94% lost 10% or more, and close to half, 47.8%, reached 20% or more
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