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They share a common hormonal driver: HPA axis dysregulation

During pregnancy, thyroid hormone is needed for myelination of the central nervous system and is essential for normal brain development

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Table adapted from Beutler ( Thus, a diminished activity of the Prdx2 antioxidant system may be a contributor to G6PD-related diseases, and this could also be dependent on the G6PD genetic variant

10.1182/blood-2004-09-3662 55 LeeY

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