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J Cell Physiol (1989) 141(1):405
In STEP-1, only 7.0% of semaglutide participants discontinued due to gastrointestinal adverse events, compared with 3.1% on placebo [2]
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Tirzepatide generally produces greater average weight loss than semaglutide and is often better tolerated, although both medications have similar gastrointestinal side-effect profiles
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