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Reduced leukocyte telomere lengths and sirtuin 1 gene expression in longterm survivors of type 1 diabetes: a Dialong substudy

Additionally, sympathetic nerve activity may further promote atherosclerosis development by enhancing inflammation and oxidative stress, which can disrupt vascular endothelial function and blood flow dynamics (Wang et al., 2023e)

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Gastrointestinal adverse effects are common but generally manageable, allowing preservation of hepatic and cardiometabolic benefits

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