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Clean the injection site with an alcohol swab, and inject subcutaneously

Inspecting the pen tells you about gross contamination or particulates, not about potency

Peak anti-inflammatory benefit appears to coincide with the period of most active weight loss (months 3 through 9), though improvements persist as long as treatment continues

Many people find that their heartburn gets better after the first few months as their body adjusts to semaglutide and they lose weight

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24, 2025, in JAMA Internal Medicine followed 308 people taking tirzepatide for 36 weeks