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Overview The retro inverso peptides (DRI peptides) are linear chains of amino acids, where the sequence is "reversed," reversing the chirality of the structure (i.e., L amino acid structure altered to D amino acid and vice versa)

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In addition to increasing miR-146a expression in OPCs, T4 remarkably also increased miR-146a expression in microglia and significantly inhibited secretion of pro-inflammatory mediators (Zhou et al., 2015), all of which may promote remyelination (Crockford, 2007)