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& Butow, R

An elevated methylmalonic acid (MMA) level has been thought to be the most direct, metabolic indicator of B12 deficiency because B12 is the only cofactor required by the enzyme that degrades MMA

One increasingly popular method gaining attention is the benefits of b-complex injection

In active/demyelinating MS lesions, the numbers of mature OLs are comparable to the numbers in the NAWM, suggesting a relative preservation of OLs, in contrast to the significant loss in chronic lesions linked with disease progression 8,9

If mood disturbances are severe or persistent, evaluation by a mental health professional is appropriate