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In vitro and in vivo effects of IGF-1 delivery strategies on tendon healing: A review

The common adverse effects include mild, transient headaches, and skin eruptions ranging from mild to severe drug reactions such as fatal StevensJohnson syndrome and toxic epidermal necrolysis, kidney and liver dysfunction, thyroid dysfunction, severe abdominal pain, and fatal complications such as air embolism or sepsis due to incorrect method of IV administration.[] TOPICAL FORMULATIONS Topical formulations of glutathione are also available in the form of cream, facewash, soap, and lotion

Glutathione is a peptide found in plants and animals

PMID 15822171

This sets off the entire HPG axis cascade, leading to increased LH and testosterone production

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