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This engineered live bacteria can activate the intestinal FXR-fibroblast growth factor 15/19 signaling pathway, alleviate vancomycin-induced bile acid accumulation and liver fibrosis

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Written informed consent was obtained from all participants after providing them with a complete description of the study

Metopimazine is a dopamine D2 receptor antagonist that exerts its antiemetic effects via the chemoreceptor trigger zone, which mediates nausea and vomiting through peripheral receptors

Acknowledgements The authors thank Prof