At Perfect B in Doral, FL, CJC-1295/Ipamorelin is our standard protocol for patients whose goals are growth hormone optimization, body composition remodeling, energy restoration, and long-term anti-aging
doi: 10.1210/jc.2016-1257
While Sermorelin is often used in younger patients or adults with growth hormone deficiencies, and occasionally in age management therapies, Tesamorelin is primarily utilized for adults, especially in the context of HIV-associated lipodystrophy
Because it is considered more receptor-selective than several earlier GH peptides, educational discussions often highlight ipamorelin for targeted GH-axis stimulation with comparatively minimal downstream influence on markers commonly associated with broader pituitary activation (such as cortisol, prolactin, and ACTH ) in experimental settings
Worked example: A 5 mg vial plus 2 mL liquid creates a 2.5 mg/mL concentration
Women should pay particular attention to monitoring IGF-1 levels and should avoid both compounds during pregnancy or while breastfeeding
