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Prolonged use can sometimes lead to skin irritation, allergic reactions, or even worsen discoloration if not properly monitored

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That does not make all compounding inappropriate, but it does make it a different category with different assumptions and risks

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Specifically, IF markedly increased the expression of glutathione peroxidase 4 (Gpx4) and heat shock protein 1 (Hspb1), while inhibiting the elevation of ferroptosis-promoting factors such as Nfe2l2, Slc7a11, and Alox8