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Pharmaceutical manufacturers learned the lesson and did a better job of testing newer formulations

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Retinoids (retinol) and corticosteroids should be avoided for 1-2 weeks before and after treatment, to avoid over-stimulation of the skin as it prepares and recovers from the laser treatment

In particular, tirzepatide 15 mg was associated with at least twofold higher odds of study drug discontinuation regardless of comparator