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L.LinJ.AldenJ.WallisL.et al (2024)

LC acts as an essential factor in the oxidation of fatty acids in the mitochondria and recent studies reported the great importance of its antioxidant and anti-inflammatory effects [,,]

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-Ketoglutarate, an intermediate metabolite of the tricarboxylic acid cycle, has been shown to suppress NLRP3 inflammasome activation and improve ovarian reserve in POI rat models (Liu K

Increased testosterone provides a negative feedback to the hypothalamus and pituitary, leading to reductions in both GnRH pulse frequency and pituitary responsiveness to GnRH, ultimately resulting in reduced gonadotropin release [37]

Additional notes How do female hormone changes impact health