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Specifically, we identified KU-57788 as a DRP1 agonist that induces excessive mitochondrial fission, which in turn activates the NRF2/SLC7A11/GSH axis as a protective response in ATC cells to mitigate its cytotoxic effects

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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Li X.C., Hu Y., Wang Z.H., Luo Y., Zhang Y., Liu X.P., Feng Q., Wang Q., Ye K., Liu G.P., et al