2000 Nov;34(12):126
Deboever N , Feldman H, Eisenberg M, Antonoff MB, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Hofstetter WL
Increased toxin-induced liver injury and fibrosis in interleukin-6-def icient mice
Lu khi s dg: Khng dng cho ng d 18 tu
A landmark study published in BMC Gastroenterology followed 29 patients with nonalcoholic fatty liver disease who received oral glutathione supplementation
The observation in this study in hepatocytes that protein-SSG formation by either GSSG accumulation or treatment with a direct S -glutathionylation induction agent resulted in IKK--SSG formation, leading to its suppression, was supported by a previous study reporting that S -glutathionylation was associated with suppressed IKK- activity in epithelial cells 41