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Research shows that maintaining 1.6 to 2.2 grams of protein per kilogram of body weight daily becomes essential during GLP-1 therapy to preserve lean mass, but when you're no longer driven by hunger, it's easy to default to easily consumed foods like crackers or smoothies that don't deliver what muscles need to survive a caloric deficit

Initial study results show that people lose a larger percentage of weight as much as 30% of their body weight when they take retatrutide compared with placebo

You may also notice other side effects common with CNS stimulants, like tremors and increased heart rate

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Diarrhea: Less common than nausea and constipation

The injections have no such timing rules