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17 Expression change of OCTN-2, OCT-1 and OCT-2 causes renal l-carnitine and organic ion imbalance to aggravate the progression of renal failure

The efficiency and safety of LeuphasylA Botox-like peptide

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[9] [10] Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, which typically diminish with continued use

10.1016/j.nbd.2011.05.013 161 IguchiY.KatsunoM.TakagiS.IshigakiS.NiwaJ.-I.HasegawaM.et al

Because the peptide simultaneously activates GLP-1R, GIPR, and GCGR, it provides a model for investigating how coordinated receptor signaling influences energy intake pathways and fat metabolism in experimental systems