youtube glutathione Is the Master Antioxidant? Here’s What Science Says Glutathione - Wikipedia

Moderate glutathione synthetase deficiency leads to hemolytic anemia and metabolic acidosis, whereas patients with a more severe deficiency also develop 5-oxoprolinuria, recurrent bacterial infections, and progressive dysfunction of the central nervous system, including mental retardation and motor functional disturbances

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Participants in this experiment complained of headache, fatigue, insomnia, intestinal disturbances, and numbness and tingling of their hands and feet (31)

Sekhar RV, Patel SG, Guthikonda AP, et al

doi: 10.1038/nbt.1504 110 YousefpoorYAmaniADivsalarAMousaviSEShakeriASabzevariJT